IMB Seminar Series - Associate Professor Sarah-Jane Dawson - 'Liquid Biopsies: Monitoring the Cancer Genome in Blood'

Event Details

Date:

Friday, 02 June 2017

Time:

12:30 pm - 1:30 pm

Room:

Queensland Bioscience Precinct Auditorium - Building 80, The University of Queensland

UQ Location:

Molecular Biosciences Building (St Lucia)

URL:

http://events.imb.uq.edu.au/seminar.php?id=1195

Event category(s):

Full Description:: Cell-free circulating DNA containing tumor-specific sequences can be identified in the plasma of cancer patients, providing a liquid biopsy alternative to tissue biopsies for monitoring cancer genetic changes over time. Circulating tumor DNA (ctDNA) analysis can allow real-time monitoring of tumor dynamics and treatment response from a simple blood test that is safe, reliable and easy to perform at regular intervals during therapy. Serial analysis of ctDNA provides a unique opportunity to study the evolving genomic landscape of a cancer during therapy, identify the early emergence of treatment resistance and guide targeted therapeutic decisions. A summary of current approaches for ctDNA analysis will be presented, together with an overview of clinical applications for the use of liquid biopsies in cancer management.