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| Family: | Picornaviridae |
| Genus: | Rhinovirus |
| Genome: | (+)ssRNA, ~7.2kb |
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Genes: |
1A(VP4),1B(VP2),1C(VP3),1D(VP1),2A(P2-A),2B(P2-B),2C(P2-C),3A(P3-A),3B(VPg),3C(protease),3D(polymerase) |
More than 100 serologicaly distinct types of human rhinovirus (HRV; Greek rhin = nose) exist within the genus Rhinovirus. The type strain of the genus is human rhinovirus type A (HRV-1A). Along with other members of the family Picornaviridae, the HRV are unenveloped viruses with a positive sense, single-stranded RNA genome that is preceded by a genome-linked proteoin (5' VPg) and terminated with a poly(A) tract (3'). The isometric nucleocapsids are 22-40nm in diameter.
Genera within the family include the Genus Enterovirus, Rhinovirus, Cardiovirus, Aphthovirus, Hepatovirus, Parechovirus, Erbovirus, Kobuvirus, Teschovirus.
Figure 1.
Schematic representation of a human rhinovirus (HRV) (+)ssRNA genome. Based on GenBank accession no. NC_001490 for HRV-QPM.
