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DNA Down Under
New section on RNA interference as a tool to block virus replication.
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Below
is a list providing examples of the many different specimen
types can be used for the detection different viruses by electron
microscopy (EM). Despite the explosion of rapid, molecular diagnostic
methods, EM still plays an important role in the detection of
new and emerging viruses and structural classifictaion of existing
viruses.
|
Virus |
Clinical
Specimen |
| |
Adenovirus |
Throat
swab/washing; Stool extract; Human brain; Liver |
| |
Astrovirus
| Stool
extract |
| |
Calicicvirus
| Stool
extract |
| |
Coronavirus
| Stool
extract; Nasopharyngeal secretion |
| |
Cytomegalovirus
| Urine;
Liver; Lymp Node |
| |
Hepatitis
A
| Stool
extract |
| |
Hepatitis
B
| Serum |
| |
Herpesvirus
| Lesion
fluid; Scab; Brain |
| |
Influenza
| Throat
washing |
| |
Minireovirus
| Nasopharyngeal
secretion; Stool |
| |
Mumps
virus
| CSF;
Nasopharyngeal secretion |
| |
Norwalk
and Norwalk-like
| Stool
extracts; Vomitus |
| |
Papovaviruses
| Urine;
Brin homogenate; Brain; Wart extract; Laryngeal papilloma |
| |
Parainfluenza
virus
| Nasopharyngeal
secretion |
| |
Parvovirus
| Serum |
| |
Poxviruses
| Lesion
fluid; Crusts; Smears |
| |
.........Vaccinia |
| |
.........Orf |
| |
.........Molluscum
contagiosum |
| |
Rotavirus |
Stool
extracts |
| |
Respiratory
syncytial virus |
Nasopharyngeal
secretion |
| |
Small
round viruses |
Stool
extracts |
| |
Varicella-zoster |
Skin
lesions; Brain; CSF |
Data
extracted from:
L.Soshiro, S.E.Miller, Application of Electron Microscopy to the
Diagnosis of Viral Infections, in Laboratory Diagnosis of Viral
Infections, 2nd ed. (E. H. Lennette), Marcel Dekker, Inc.,
New York, New York, 1992, Chapter 2.
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