Haematological Reference Ranges

Red Cell Count (RCC): Male: 5.5 +/- 1.0 x 1012/L (4.5-6.5 x 1012/L)
  Female: 4.8 +/- 1.0 x 1012/L (3.8-5.8 x 1012/L)
  Infant
(Full term, iron sufficient, cord blood):
5.0 +/- 1.0 x 1012/L
(4.0-6.0 x 1012/L)
Haemoglobin (Hb): Male: 155 +/- 25 g/L (130-180g/L)
  Female: 140 +/- 25g/L (115-165g/L)
  Infant:
    0-2 months: -
    2-4 months: 100g/L (lower in premature babies 1.0kg-80g/L; 1.5kg-2.0-90g/L)
    4-6 months: 105g/L
    6 months-2 years: 110g/L
    2-5 years: 110g/L
    5-9 years: 115g/L
    9-12 years: 120 g/L
 
Packed Cell Volume (Hct): Male: 0.47 +/- 0.07 L/L (0.40-0.54 L/L)
  Female: 0.42 +/- 0.05L/L (0.37-0.47 L/L)
Mean Cell Volume (MCV): Adult: 86 +/- 10 fL (76-96 fL)
  Infant:
    0-2 months: Macrocytes
    2-4 months: 80 fL
    4-6 months: 72 fL
    6 months-2 years: 70 fL
    2-5 years: 73 fL
    5-9 years: 75 fL
    9-12 years: 76 fL
 
Mean Cell Hamoglobin (MCH): Adult: 29.5 +/- 2.5fL (27-32 pg)
Mean Cell Haemoglobin Concentration (MCHC): Adult/Children: 325 +/- 25 g/L (300-350 g/L)
Red Cell Distribution Width (RDW): 11.5-14.5%  
Leucocyte/White Cell Count: Adult: 7.5 +/- 3.5 x 109/L (4-11x109/L)
Differential Leucocyte Count ("Diff"): Adult:
  • Neutrophils: 2.0-7.5x109/L (40-75%)
  • Lymphocytes: 1.5-4.0x109/L (20-45%)
  • Monocytes: 0.2-0.8x109/L (2-10%)
  • Eosinophils:0.04-0.4x109/L (1-6%)
  • Basophils: less than 0.01-0.1x109/L (less than 1%)
 
  Infant:

    Lymphocytes
    0-6 months: less than 15.0x109/L
    0.5-1 years: less than 11.0x109/L
    1-4 years: less than 9.0x109/L
    4-10 years: less than 6.5x109/L
    10-14 years: less than 6.0x109/L
    Neutrophils:
    Up to 20x109/L on the first day only
    Lower lmits of normal:
    less than 3 months: greater than 2.5.0x109/L
    3 months-3 years: greater than 2.0x109/L
    3-5 years: greater than 1.5x109/L
    Eosinophils:
    less than 5 years: less than 0.7x109/L
    greater than 5 years: less than 0.5x109/L
 
Platelet Count (Plt): Adult: 150-400 x 109/L  
Reticulocyte Count: Adult: 25-85 x 109/L (0.2-2.0%)
Erythrocyte Sedimentation Rate (ESR): Male: 2-10 mm/hr  
  Female: 2-15 mm/hr  
Bone Marrow Cellularity: 25-75% Cells  
Fibrinogen: 1-4g/L
Bleeding Time (BT): Modified Ivy Technique: 1.5-4.5 min
  Standardized Template Method: 2.5-9.5 min
Activated Partial Thromboplastin Time (aPTT): Automated aPTT Reagent: 25-43 sec
Plasma Volume: Adult: 50 +/- 10mL/kg bodyweight  
Red Cell Mass/Volume: Male: 30 +/- 5mL/kg bodyweight  
  Female: 25 +/- 5mL/kg bodyweight  
Acute Leukaemia Distribution: AML:
  • 20% of young children (2-10) with leukaemia
  • 40% of adults (especially >50yr) with leukaemia
 
  ALL:
  • 80% of young children with leukaemia
  • 10-20% of adults with leukaemia
 
Chronic Leukaemia Distribution: CML:
  • Rare in young children with leukaemia
  • 20-25% of adults with leukaemia
 
  CLL:
  • Virtually unheard of in young children
  • 25-30% of adults with leukaemia
 
Shift To The Left: N(seg) : N(nonseg) = 1 : 0.1-0.3
Immature cells include:
    Blasts, promyelocytes, myelocytes,
    metamyelocytes, pronormoblasts, basophilic normoblasts,
    polychromatic normoblasts and
    orthochromatic normoblasts
Shift To The Right/Hypersegmented: Neutrophils:
  • More than 5% have 5 lobes / More than 5% have 6 or more lobes
  Eosinophils:
  • More than 5% have 3 lobes / More than 5% have 4 or more lobes
New look for June 2003