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The Imaging and Modelling Group is a sub-group of the Therapeutics Research Unit. The Imaging and Modelling Group focuses on the contribution that the physical and mathematical sciences can make to research undertaken at the TRU. This includes the development of pharmacokinetic models to describe transdermal permeation, using traditional statistical methods (in conjunction with the Topical Drug Delivery Group). However, it also incorporates the use of cutting-edge methods and technologies to improve our understanding of transdermal permeation, including molecular simulation and multiphoton (fluorescence) microscopy.
Research interests include:
- Pharmacological modelling of transdermal permeation processes
- Molecular modelling of transport processes in the stratum corneum
- Application of multiphoton microscopy to transdermal penetration studie
- Application of multiphoton microscopy in skin pathology assessment
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