Drug Analysis and Medicinal Chemistry Group - UQ reSEARCHers (Publications)

	Publication

2009	Li, Peng, Wang, Guang-Ji, Robertson, Thomas A. and Roberts, Michael S. (2009) Liver transporters in hepatic drug disposition: An update. Current Drug Metabolism, 10 5: 482-498.
	Drug transporters expressed on the hepatocyte membrane play an important role in hepatic drug disposition. In the last two decades, systematic research has resulted in a better understanding of the diversity, expression and substrate specificities of drug transporters in the liver. Here we review recent studies on the role of transporters in drug-drug interactions and disease states such as cirrhosis. We conclude the review by considering techniques and model systems used to study hepatic transporters, including the latest technological developments such as multiphoton microscopy.
	Mr Li Peng, Dr Thomas Robertson, Professor Michael Roberts
eSpace Record:	http://espace.library.uq.edu.au/view/UQ:201096

Links:	Article DOI - full text from publisher
Keywords:	Hepatocyte membrane, Drug disposition, Liver