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Professor Alan Mark   
Prof Research Fellow Arc Dora

Equina toxin II

Equina toxin II
Amyloid membrane interactions.

Amyloid membrane interactions.
One possible way amyloid fibrils found in various neurodegenerative diseases kill cell is by interacting with cell membranes. Here a fibril formed by the SIP35 peptide is shown bound to a DPPC membrane (image David Poger).
Vesical_fusion

Vesical_fusion
Snapshots from a simulation of the fusion of two small phospholipid vesicles in near atomic resolution (see Marrink and Mark 2003, JACS, 125, 11144).
Alan E. Mark

Alan E. Mark
Alan E. Mark
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