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Dr Dianne Keough   
Research Officer

 Publications
  1999  Purification and characterization of Plasmodium falciparum hypoxanthine-guanine-xanthine phospho-ribosyltransferase and comparison with the human enzyme
  2006  Lead compounds for antimalarial chemotherapy: Purine base analogs discriminate between human and P-falciparum 6-oxopurine phosphoribosyltransferases
  2005  Normal HPRT coding region in a male with gout due to HPRT deficiency (Brief Communication)
  2005  The crystal structure of free human hypoxanthineguanine phosphoribosyltransferase reveals extensive conformational plasticity throughout the catalytic cycle
  2002  Crystal structures of free, IMP-, and GMP-bound Escherichia coli hypoxanthine phosphoribosyltransferase
  2002  Substrate analogues discriminate between human and Plasmodium falciparum 6-oxopurine phosphoribosyltransferases
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