| Undergrad/Postgrad | EXPERIMENTAL ANALYSIS OF AXON GUIDANCE IN NEURAL DEVELOPMENT |
| | We are using a range of experimental assays to understand the mechanisms by which nerve fibres detect and respond to molecular gradients. |
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| Undergrad/Postgrad | MATHEMATICAL/COMPUTATIONAL MODELS OF VISUAL SYSTEM WIRING |
| | Through collaborations with experimental labs both nationally and
internationally we have access to a range of data regarding how
patterns of visual input during neural development affect the
structure of the visual brain. We would like to build quantitative
models which both characterize the statistics of normal and abnormal
visual inputs, and which explain how these statistics influence the
way our brain develops. |
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| Postgrad | MATHEMATICAL/COMPUTATIONAL MODELS OF AXONAL CHEMOTAXIS |
| | We would like to build quantitative models to explain the behaviour of
growing axons in gradients, particularly from our own experiments. We
are especially interested in "Ideal Observer" (Bayesian) models of how
axons might extract small gradient signals from noisy measurements. |
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| Undergrad/Postgrad | ANALYSIS OF NEURAL DATA |
| | We have developed a uniquely quantitative
experimental assay for studying the response of axons in chemical
gradients. These experiments produce a large amount of data in the
form of images and movies of growing axons. Extracting quantitative
information from these is a challenging task due to both the
complexity of the underlying phenomena and noise in the processes of
data acquisition.
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