How fetal stem cells repair tissues in mother and baby, and how to treat transfusion syndromes in monochorionic twins.
Nicholas Fisk was the inaugural Director of University of Queensland's new state of the art $70M Centre for Clinical Research on the Herston campus, before becoming Executive Dean of Health Sciences in 2010. He practices as a maternal-fetal medicine specialist / high risk obstetrician at the Royal Brisbane and Women's Hospital, and maintains a research group in UQCCR.
Between 1992-2007 he was Professor of Obstetrics /Fetal Medicine at Imperial College & Queen Charlotte's Hospital, London, where his laboratory and clinical research program achieved an international reputation in fetal diagnosis and treatment. His main research interests have been in human fetal mesenchymal stem cell biology and monochorionic multiple pregnancy, but also spanned non-invasive prenatal diagnosis, fetal nociception, caesarean section, preterm labour, obstetric ultrasound and drug development in obstetrics. A fetal-medicine subspecialist with an MBA and a PhD in fetal physiology, he has authored nearly 400 publications, and is a past President of the International Fetal Medicine and Surgery Society. He reviews for numerous international grant bodies, and is a member of several editorial boards including PLoS Medicine.
He is passionate about the opportunities offered in UQCCR, to drive clinical research in a "bench to bedside" and "bedside to bench" environment, to link wet and dry laboratories with patients, and basic with clinical scientists, and to foster the training of tomorrow's cadre of translational researchers. Organic talent within UQCCR's main themes of clinical neuroscience, cancer and tissue repair, is being augmented by appointment of international researchers and linked by core cross cutting themes in clinical trials & outcomes, perinatal medicine and stem cells.
His own experimental fetal medicine group works on the role of fetal mesenchymal stem cells in tissue repair, both the development stem cell transplantation to repair debilitating early onset genetic disease, and their wider application to childhood and adult diseases. His clinical fetal medicine group in collaboration with colleagues in the hospital's Centre for Advanced Prenatal Care works on the twin twin transfusion syndromes, in particular optimising results of current laser and other therapies.
||Science and Technology: Stem Cell Biology, Medical: Fetus, Medical: Placenta, Medical: Pregnancy Disorders, Medical: Stem Cell, Medical: Perinatal Disorders, Medical: Stillbirth, Medical: Ultrasound, Medical: Birth/Congenital Defects, Medical: Osteogenesis Imperfecta, Medical: Biomedical Research, Multidisciplinary, Medical: Women's Health, Medical: Obstetrics/Gynecology