| 2007 - 2010
| Synaptic Dysfunction in Alzheimer's Disease |
| | This project has been funded by the Alzheimer's Association (U.S.) and is being conducted in collaboration with Dr Rudi Tannenberg and A/Prof Peter Dodd in Dr Dodd's laboratory in the School of Microbial and Molecular Sciences. |
| Keywords: | Alzheimer's disease; dementia; synapse; synaptic; brain; |
|
| 2007 - 2009
| Anxiety & Depression During Cognitive Ageing |
| | This 3-year NHMRC-funded study will look at the emergence of syndromal and sub-syndromal anxiety and depression in a cohort of 511 women from the LAW Study being conducted at the Royal Brisbane & Women's Hospital.
For further information on this study contact Liz Arnold on 07 3365 5147. |
| Keywords: | Ageing; Cognition; Anxiety; Depression |
|
| 2004 - 2009
| Neuropsychiatric Symptoms in Alzheimer's Disease |
| | Data collection has commenced on a prospective study of predictors of incident neuropsychiatric symptoms in patients with late-onset Alzheimer disease. This research project will run for about five or six years - two to three years to recruit the participants and 30 months to complete the longitudinal data collection on each participant.
This work is being funded by a generous bequest via the RBWH Research Foundation.
For further information on this project, please contact Liz Arnold on (07) 3365 5147. |
| Keywords: | Alzheimer's disease; dementia; behavior; neuropsychiatry |
|
| 2007 - 2017
| International collaborations using interRAI |
| | We are engaged in clinical validation of the interRAI instrument for cross-national data collection in older person's mental health services.
For further information please contact Gerard Byrne on 07 3365 5148. |
| Keywords: | interRAI; dementia; anxiety; depression; psychosis |
|
| 2004
| Clinical Drug Trials for Alzheimer's disease |
| | We are currently involved in several clinical pharmaceutical trials of new drugs or new formulations of existing drugs for the treatment of mild to moderate Alzheimer's disease.
For further information on these projects, please contact Liz Arnold on 3365 5147. |
| Keywords: | Alzheimer's disease; dementia; treatment; clinical trial |
|
| 2003
| Measurement of Anxiety in Older People |
| | This program of collaborative research with Dr Nancy Pachana (School of Psychology) has been underway for about 12 months. The aim of this program is to develop a novel measure of generalised anxiety for use in older people. No such measure currently exists. We plan to use factor analysis and discriminant function analysis to shrink the current draft 60 item scale to 20 or 30 items for everyday use. We will then publish the scale in the public domain. Subsequently, we will use the scale to investigate genetic and other predictors of generalised anxiety in older people. Ultimately, we hope to be able to use the scale as an outcome measure for treatment trials in older people. We anticipate that this research program will continue for 5-10 years. |
| Keywords: | anxiety; elderly |
|
| 2003
| Development of Cogni-Screen: A Diagnostic System for Dementia |
| | In a collaborative project with Prof Mike Humphreys (Key Centre for Human Factors & Applied Cognitive Psychology), Dr Nancy Pachana (School of Psychology) & Prof Chris Del Mar (Griffith University) we are developing a computerised diagnostic system for dementia. This system involves a web-based real-time system using speech recognition software. The project has been funded by grants from the NHMRC and the Telstra Broadband Development Fund. |
| Keywords: | cognitive impairment; dementia; Alzheimer's disease |
|
| 2001 - 2004
| Depression in Stroke Patients |
| | Data collection for this three-year project on the value of clinical guidelines for the diagnosis and management of major depression in stroke patients is almost completed. This Queensland Health funded project involved the development and implementation of clinical guidelines within the RBWH Stroke Service. To measure the clinical utility of these guidelines, two cohorts of 100 stroke patients have been enrolled: one prior to the development of the guidelines and one following their introduction. |
| Keywords: | depression; guidelines; stroke |
|
|
| Personality and Depression following Stroke |
