Contact Details

Position: 
ARC Future Fellow, Senior Lecturer
Room: 
318
Mail: 
School of Biomedical Sciences, The University of Queensland, BNE, QUEENSLAND 4072
Telephone: 
+61 3365 2299
Facsimile: 
+61 7 3365 1766
Biography: 

Dr Thiruma V. Arumugam (Garrie) received his Bachelor's of Medical Science (Hons) from the University of Sydney and a Ph.D. in Pharmacology from the University of Queensland. He moved to Louisiana State University Health Sciences Center in Shreveport, Louisiana in 2003 to complete a Post Doctoral fellowship with the highly cited Professor D. Neil Granger on the role of T cells in Stroke. Dr. Arumugam then accepted a Post Doctoral position in the laboratory of highly cited Professor. Mark P. Mattson's at the National Institute on Aging, NIH, where he studied the novel mechanisms of ischemic stroke injury. After 3 years of training at NIH, Dr Arumugam took a tenure-earning faculty position in the Department of Pharmaceutical Sciences at the Texas Tech University Health Sciences Center (2007-2009). Dr Arumugam moved to Australia and began as a senior lecturer at the UQ School of Biomedical Sciences, in January 2009.

Research Interests: 

Mechanisms of Ischaemic Stroke: Ischaemic stroke is a devastating disease that represents the second leading cause of death in Australia. Ischaemic stroke causes damage and death of neurons in the perfusion territory of the affected blood vessel. The neurodegenerative mechanism involves metabolic and oxidative stress, excitotoxicity and apoptosis, and inflammatory processes including microglia activation and infiltration of activated leukocytes.

A primary focus of our laboratory is to understand the cellular and molecular mechanisms and to study therapeutic targets to treat ischaemic stroke injury. Toward this end, we have developed in vitro and in vivo models of ischaemic stroke.

Associations: 

Society for Neuroscience

Grants: 
CIA: Role of FcR in Ischaemic Stroke Induced Neuronal Cell Death
Grant Body: UQ ECR
Grant Period: 2010-2011
Value: $32,000

CIA: Role of Adiponectin in Ischaemic Stroke Induced Neuronal Cell Death
Grant Body: UQ NSRSF
Grant Period: 2009-2010
Value: $12,000

CIA: Notch-NFkappaB in Neuronal Cell Death
Grant Body: Australian Heart Foundation
Grant Period: 2010-2011
Value: $129,000

CIA: Gamma-Secretase inhibitors as novel pharmacological agents to target stroke induced brain injury
Grant Body: NH&MRC
Grant Period: 2011-2013
Value: $ 426,273

CIA: Novel pharmacological agents to target stroke induced brain injury
Grant Body: ARC (Future Fellowship)
Grant Period: 2011-2014
Value: $706,552

CIB: TNF traffic and secretion in astrocytes and microglial cells
Grant Body: NH&MRC
Grant Period: 2011-2013
Value: $ 565,048

CIB: A systems biology approach to elucidate triplet repeat expansion associated genetic defects
Grant Body: NH&MRC
Grant Period: 2011-2013
Value: $ 726,284

CIC: Does a Novel Estrogen Receptor Worsen Stroke Outcome?
Grant Body: NH&MRC
Grant Period: 2011-2013
Value: $ 506,706

CIC: Aldosterone and the Mineralocorticoid Receptor in Cerebrovascular Disease
Grant Body: Australian Heart Foundation
Grant Period: 2011-2012
Value: $129,000
Qualifications and Awards: 

BMedSc (Hons) USyd, PhD UQ