Dr James (Jim) Pickles

Position

Research Fellow | Honorary Reader

Qualifications and Awards

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Affiliations

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Associations

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Contact Details

Biography

Jim Pickles is the Head of the Hearing Unit. He was previously Reader in Auditory Physiology in the Department of Physiology at the University of Birmingham, UK, and moved to the Vision Touch and Hearing Research Centre in 1989. He has been financed by a Garnett Passe and Rodney Williams Memorial Foundation Senior Research Fellowship. Before that, he was an Australian Senior Research Fellow of the Australian Research Council. He is the author of An Introduction to the Physiology of Hearing (3rd ed, Emerald, 2008).

Research Interests

Cochlear Function
Dr Jim Pickles' research concentrates on the function, development, regeneration, and pathology of the hair cells of the cochlea. The work is a development of the discovery of 'tip links', fine macromolecular strands that interconnect the tips of the mechanosensitive hairs or stereocilia on the cells, enabling the cells to detect sound. Current work concerns mitochondrial contributions to hearing loss in ageing, and gene array analysis of acoustic neuroma. For my main Web site on my research, please go to: http://www.uq.edu.au/~pljpickl

Selected Publications

Mutation in mitochondrial DNA as a cause of presbyacusis.
Audiol Neurootol. 9, 23-33.
Pickles J.O. (2004)

Expression of Ephs and ephrins in developing mouse inner ear.
Hear Res. 178, 44-51.
Pickles J.O. (2003)

Temporal and spatial expression of fibroblast growth factor receptor 4 isoforms in murine tissues.
Histochem. J. 34, 291-297.155, 54-62
Cool, S.M., Sayer, R.E., van Heumen, W.R.A., Pickles, J.O., Nurcombe, V. (2002)

The lateral line canal sensory organs of the Epaulette Shark (Hemiscyllium ocellatum).
Acta Zool. (Stockh.). 83, 337-343.
Joergensen, J.M., Pickles, J.O. (2002)

Complementary and layered expression of Ephs and ephrins in developing mouse inner ear.
J. Comp. Neurol. 449 (3), 207-216.
Pickles, J.O., Claxton, C. and van Heumen, W.R.A. (2002)

Grants

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