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 Pharmacology


Group Strengths

Membership



Dr Thiruma Arumugam

Understanding of molecular and cellular mechanisms of neuronal cell death following ischemic stroke.

 

Dr Mary-Louise Roy Manchadi
Neuronal and cardiac ion channels and their modulation by natural toxins and medicinal compounds.


Assoc. Prof. Lindsay Brown
Testing interventions such as diet, drugs and exercise to prevent or reverse the cardiovascular changes in chronic diseases.  Rat models of these important human diseases, such as diet-induced diabetes and chronic hypertension leading to heart failure.

Prof. Mick McManus

The structure, function and regulation of enzymes involved in the metabolism of drugs and chemical carcinogens.


Assoc. Prof. Elizabeth Gillam

Directed evolution of cytochrome P450 enzymes as designer catalysts for the pharmaceutical industry. Roles of P450s in mediating the adverse effects of herbal medicines.


Prof. Rod Minchin

Role of different proteins in normal and cancer cells


Assoc. Prof. Lesley Lluka

Regulation of transporters for noradrenaline, dopamine and serotonin in depression, schizophrenia and drug abuse. Molecular structure-activity relationships of the noradrenaline transporter.


Prof. Stephen Taylor
Immunopharmacology; development of new classes of anti-inflammatory drugs.

 

Dr Karin Borges
Novel approaches to prevent seizures and the development of epilepsy in rodent models focussing on anti-inflamattory treaments.
 


Dr Ricarda Thier
Xenobiotic metabolism (esp. glutathione transferases) in toxicology and pharmacology. Gene-environment interactions. Indirect genotoxicity via cytoskeletal proteins.
 

Dr Trent Woodruff
Role of Inflammation in Neurodegenerative Disease