Potential Research Projects - Overview
Within the Pharmacometrics Area
- Establishing PK and PD models for antibiotics used in special pediatric populations
(Dr Stefanie Hennig) - Finding the influences on antibiotic resistance in patients with cystic fibrosis
(Dr Stefanie Hennig) - How to dose chemotherapy in obese patients? To cap or not to cap?
(Dr Stefanie Hennig) - Optimal experimental design and its application for clinical studies
(Dr Stefanie Hennig) - PKPD and disease progression modeling in patients with cystic fibrosis
(Dr Stefanie Hennig) - PKPD and disease progression modelling of gabapentin and pregabalin for chronic pain
(Dr Stefanie Hennig) - PKPD modelling of immunosuppressive agents in kidney transplants patients
(Dr Stefanie Hennig) - Population pharmacokinetics in children, especially premature infants
(Associate Professor Bruce Charles) - Population pharmacokinetic and pharmacodynamic meta-analysis of pre-existing data
(Dr Stefanie Hennig) - Population pharmacokinetics in chemotherapy
(Associate Professor Bruce Charles) - Population pharmacokinetics and pharmacodynamics of the newer immunosuppressant drug
(Professor Sue Tett) - Towards optimal dosing of new immunosuppressant drugs in solid organ transplants
(Professor Sue Tett and Dr Christine Staatz)
Within the Pharmacy Education Area
No projects currently offered
Within the Quality Use of Medicines Area
- A study to investigate and identify risk factors associated with trace element deficiency in chronic diseases
(Dr Karen Whitfield) - A study to investigate and identify risk factors associated with trace element deficiency in full term and premature neonates
(Dr Karen Whitfield) - A study to investigate optimal dosing of ibuprofen for the management of patent ductus arteriosus in neonates
(Dr Karen Whitfield) - A study to investigate optimal dosing strategies of propofol for short term procedures in neonates
(Dr Karen Whitfield) - A study to investigate the optimal management of phantom limb pain
(Dr Karen Whitfield) - Adherance and its relationship to patient beliefs towards their medicines
(Dr Neil Cottrell) - Administration and adherence to paediatric medicine regimens
(Dr Therese Kairuz) - Drugs levels in breast milk - this will involve investigating specific medications and analysis of levels in breast milk and any clinical implications for the infant
(Dr Karen Whitfield) - Drug usage evaluation - influencing prescription medication use across jurisdictional boundaries (eg. hospital/community; public/private) using multi-disciplinary teams
(Professor Sue Tett) - Drug utilisation and pharmaco-epidemiology in Australia
(Dr Therese Kairuz) - Factors affecting prescribing and use of medicines, including the influence of various marketing strategies (eg. free prescription medicines samples), the influence of location (eg. rural, remote) and issues around consumer motivation and choice
(Professor Sue Tett) - International comparisons of medicines use, investigating pharmaceutical policy and other influences on usage
(Professor Sue Tett) - Key influences on the safe and effective prescribing and use of medicines
(A/Prof. Lisa Nissen) - Medication taking behaviour during pregnancy and breast feeding (prescription and non prescription medications)
(Dr Karen Whitfield) - Modifying solid dosage forms for patients with difficulties swallowing their medications: Quality use of medicines issues
(A/Prof. Lisa Nissen and Dr Kathryn Steadman) - Patient compliance and perceptions of prescribed medicines
(Dr Therese Kairuz)
Within the Therapeutic Targeting Area
- Approaches to therapeutic targeting of MYB in leukaemia and other cancers
(Prof. Tom Gonda) - Bioanalysis, bioavailability and disposition of phytochemicals from tropical fruits
(Prof. Nick Shaw , Dr Amitha Hewavitharana and Professor Mike Gidley) - Biomolecular quantitation in LC-MS-MS: investigation of factors affecting accuracy
(Prof. Nick Shaw and Dr Amitha Hewavitharana) - Calcium homeostasis in cancer: identification and characterization of novel drug targets
(Prof. Greg Monteith) - Caveolae and angiogenesis
(Dr Marie-Odile Parat) - Caveolar proteins and cancer
(Dr Marie-Odile Parat) - Caveolae and tumour cell response to pressure
(Dr Marie-Odile Parat) - Charged liposaccharide based drug delivery systems
(Prof. Istvan Toth) - Compounding and compounded medicines: issues and quality
(A/Prof. Kathryn Steadman) -
Delivery of pilocarpine to the mouth mucosa; development and testing of potential formulae and products
(A/Prof. Kathryn Steadman, Professor Geoffrey Mitchell, Dr Hugh Senior) - Design, synthesis and evaluation of novel molecules for the treatment of Alzheimer's disease
(Dr Ben Ross) - Development and application of high-throughput functional gene-based screening
(Prof. Tom Gonda) - Development of novel reducible gene delivery systems
(Dr Harendra [Harry] Parekh) - Diabetic neuropathy: mechanistic studies
(Prof. Maree Smith) - Evoluation of novel analgesic agents for the relief of neuropathy pain
(Prof. Maree Smith) - Gene delivery systems
(Prof. Istvan Toth) - Gene delivery therapeutics for age-related macular degeneration
(Dr Harendra [Harry] Parekh) - Identification and characterization of novel ion and drug transporters and the design of novel high throughput screening assays for new pharmaceuticals
(Prof. Greg Monteith) - Identification and functional characterisation of MYB target genes
(Prof. Tom Gonda) - Mammary gland development and lactation: Calcium transport
(Prof. Sarah Roberts-Thomson) - Medicinal and Biomolecular chemistry of Alzeimer's disease
(Dr Ben Ross) - Modifying solid dosage forms: effects on therapeutic outcomes
(A/Prof. Kathryn Steadman and A/Prof. Lisa Nissen) - Molecular approaches for breast cancer research
(Prof. Sarah Roberts-Thomson) - Morphine and metastasis
(Dr Marie-Odile Parat) - Myeloid leukaemia gene discovery
(Prof. Tom Gonda) - Novel immunoadjuvants for vaccine delivery
(Prof. Istvan Toth) - Painful diabetic neuropathy: towards improved drug treatments
(Prof. Maree Smith) - Peripheral mechanisms of analgesia and the involvement of the immune system
(Dr Peter Cabot) - Pharmaceutical chemistry of prodrugs: Design, synthesis & evaluation
(Dr Ben Ross) - Physiological regulation and the role of calcium transporters
(Prof. Greg Monteith) - Plant-derived bioactives: targeted delivery using modern techniques
(Dr Harendra [Harry] Parekh) - Plant proteins as drug delivery polymers
(A/Prof. Kathryn Steadman) - Quantitation of markers of oxidative stress using LC-MS-MS
(A/Prof Jeff Coombes, Prof. Nick Shaw and Dr Amitha Hewavitharana) - Regulation of MYB expression by transcriptional elongation: mechanism and potential for targeting in cancer
(Prof. Tom Gonda) - Role of caveolar proteins in glioblastoma
(Dr Marie-Odile Parat) - Role of MYB in human breast cancer
(Prof. Tom Gonda) -
Seed mucilages as pharmaceutical agents in drug delivery
(A/Prof. Kathryn Steadman and A/Prof. Jason Stokes) - Screening of marine bacteria for antibiotics and novel drugs
(Dr Amitha Hewavitharana, Prof. Nick Shaw and A/Prof J. Fuerst) - Studies of xenobiotic metabolism and small molecule biomarkers using LC-MS-MS
(Prof. Nick Shaw , Dr Amitha Hewavitharana and Dr Peter Cabot) - Study of the metabolism of opioid peptides using LC/MS/MS and the role of opioid metaboites in inflammatory disease
(Prof. Nick Shaw , Dr Amitha Hewavitharana and Dr Peter Cabot) - Synthesis and application of dendrimers in RNAi
(Dr Harendra [Harry] Parekh)
