The Ethics of Germ Line Gene Manipulation

Overview

Germ line gene manipulation (GLGM) is the alteration of the genomic content of gametes or zygotes via the insertion of a gene, or genes, into the genome of germ cells. Any such alterations affect the genomic content of future generations. Ethical issues raised by GLGM primarily relate to slippery slope arguments, the moral status of an embryo and intergenerational consent. Concerns about the safety and efficacy of the procedure are also pertinent. This project was originally undertaken as part of an Honours degree in Philosophy in 2000. Since then, the work has been revised for future publication as well as for distribution as an OPPE factsheet.

OPPE Staff

Lucy Carter

Status

Completed

Outcomes

The work has been summarised in an OPPE factsheet.
The work has also been published in a peer-reviewed journal:

Carter, L. The ethics of germ line gene modification - A five dimensional debate, Monash Bioethics Review, 2002, 21(4): 66-81.

Funding

OPPE

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Last updated: 9 July 2003