Biochemistry Alumni Lecture: Genetics, Genomics and Biochemistry of Innate Immunity

Event Details

Date:

Wednesday, 12 September 2018

Time:

3:00 pm - 5:00 pm

Room:

Seminar Room

UQ Location:

Queensland Bioscience Precinct (St Lucia)

URL:

https://www.vision6.com.au/forms/s/4363ed0/23336/510590.html

Event category(s):

Full Description:: In the face of an infectious disease challenge, individuals may be susceptible (succumb to challenge), resistant (clear the pathogen without pathology) or resilient (develop effective immunity and recover).

This talk will introduce the biology of macrophages, cells of the immune system that are a front-line defense against pathogens and also contribute to many aspects of homeostasis and physiology. Because of their roles in immunity, genes expressed in macrophages evolve rapidly in the face of pathogen selection, and entire pathways differ between species and between individuals within a species.

Professor David Hume will discuss the ways in which we have identified and annotated macrophage-specific genes in multiple species, and the many species-specific or individual genetic variations that contribute to variations in response to infectious disease challenge. He will also discuss the way in which the same genetic variations underpin susceptibility to inflammatory disease in humans.

Please register to attend this event: http://ems.gs/3iGO0jVbliD