Event Details

Wednesday, 15 February 2017
11:00 am - 12:00 pm
QBI Level 7 Auditorium
UQ Location:
Queensland Brain Institute (St Lucia)
Event category(s):

Event Contact

Ms Deirdre Wilson
334 66300
Org. Unit:
Queensland Brain Institute

Event Description

Full Description:
Professor Geoff Faulkner
Queensland Brain Institute, and Mater Research Institute, University of Queensland

Title: Somatic L1 mosaicism: 'dark matter' in mammalian genetics

Abstract: Professor Geoff Faulkner's core research seeks to understand the role of LINE-1 (L1) retrotransposons, a type of “mobile DNA”, in causing genetic mosaicism in stem cells and neurons. This L1 variation may be a fundamental aspect of healthy brain function, and appears to change in neurological diseases, including Alzheimer’s disease, Rett syndrome and schizophrenia. In this talk, he will discuss new approaches to identify L1 retrotransposon insertions in individual mammalian cells, as well as recent results suggesting these L1 variants occur early in neurodevelopment, generating common somatic genome mosaicism in the mammalian brain.

Directions to UQ

Google Map:
To St Lucia Campus, UQ Ipswich, and UQ Gatton.

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