QBI Neuroscience Seminar: Using imaging and genetics to unravel the complexity of the human brain
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- Speaker: Associate Professor Margie Wright
Queensland Brain Institute, The University of Queensland
Title: Using imaging and genetics to unravel the complexity of the human brain
Abstract:
Availability of novel imaging data from large genetically informative samples is vital to gain insight into the complex interplay between genetic and environmental risk/protective factors on the human brain, and provide a window into the biological mechanisms leading to brain diseases. In my seminar I will i) present our findings mapping the genetic and environmental influences on brain phenotypes, and the relationships between brain measures and specific mental health phenotypes, ii) present our work from the ENIGMA consortium, which has identified genetic loci that affect brain volumes and factors that modulate disease affects, and iii) describe a new study using imaging to track developmental changes in the brain through adolescence, how these neurodevelopmental changes contribute to cognitive, emotional, and social well being, and the role of genetic factors in this relationship. These large data sets of brain imaging and genetic data enable analyses on a new scale and may help detect deviations from normal development or aging.
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