Event Details

Friday, 10 June 2016
12:30 pm - 1:30 pm
2.171, QBP Auditorium
UQ Location:
Queensland Bioscience Precinct (St Lucia)
Event category(s):

Event Contact

Professor David Craik
334 62019
Org. Unit:
Institute for Molecular Bioscience

Event Description

Full Description:
Innate immunity proteins form the first line of defence against potential pathogens in animals and plants. Most research has focused on those with antibacterial properties, but there is an increasing need for effective antifungal agents for use in agriculture and in the clinic.

The first part of this talk will focus on the discovery of new antifungal peptides from plants, their mechanism of action and potential applications for disease control in plants. One of these plant defensins,NaD1, is active against both filamentous fungi and yeast and acts via a three step process that involves interaction with the cell wall, followed by specific interaction with membrane lipids, membrane permeabilisation and entry into the cytoplasm where it initiates cell death. The second part of the talk will describe the potential of plant defensins as effective and robust treatments for fungal infections in humans.

I will describe why the novel plant defensin HXP124 is an excellent candidate for developing a fast, effective topical treatment for fungal nail infections (onychomycosis).

*SEATING IS LIMITED. Please arrive early to avoid disappointment.*

Directions to UQ

Google Map:
To St Lucia Campus, UQ Ipswich, and UQ Gatton.

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