QBI Seminar: Using an expanded genetic code to study ion channel function & pharmacology at the atomic level

Event Details

Date:

Wednesday, 28 October 2015 - Wednesday, 28 October 2015

Time:

12:00 pm - 1:00 pm

Room:

QBI Level 7 Auditorium

UQ Location:

Queensland Brain Institute (St Lucia)

URL:

http://www.qbi.uq.edu.au/neuroscience-seminars

Event category(s):

Full Description:: A/Professor Stephan Pless
Department of Drug Design and Pharmacology,University of Copenhagen, Denmark
Title:
Using an expanded genetic code to study ion channel function & pharmacology at the atomic level
Abstract:
Ion channels play crucial roles in the nervous system by initiating and propagating electrical signals. Consequently, acquired or inherited dysfunctions are associated with numerous diseases, necessitating a thorough understanding of their molecular function and pharmacology. Here, I will present data on how an expanded genetic code can be used to incorporate synthetic amino acids in ion channels in order to assess their function and pharmacology with unprecedented detail.