QBI Seminar: Where the tortoise and the hare meet – clathrin & adaptors in synaptic vesicle cycling

Event Details

Date:

Friday, 14 August 2015 - Friday, 14 August 2015

Time:

2:00 pm - 3:00 pm

Room:

QBI Level 7 Auditorium

UQ Location:

Queensland Brain Institute (St Lucia)

URL:

http://www.qbi.uq.edu.au/neuroscience-seminars

Event category(s):

Full Description:: Professor Volker Haucke,
Department of Molecular Pharmacology and Cell Biology, Freie Universitat, Berlin, Germany

Title: Where the tortoise and the hare meet – clathrin & adaptors in synaptic vesicle cycling

Abstract:
The function of the nervous system depends on the exocytotic release of neurotransmitter from synaptic vesicles (SVs). To sustain neurotransmission SV membranes need to be retrieved and SVs have to be reformed locally within presynaptic nerve terminals. In spite of more than forty years of research the mechanisms underlying presynaptic membrane retrieval and SV recycling remain controversial. In my talk I will present latest data regarding the molecular mechanisms of presynaptic membrane retrieval and SV reformation and the role of endocytic proteins in these processes.