CAI Seminar: Open Field PET
Event Details
- Date:
- Tuesday, 19 May 2015
- Time:
- 2:00 pm - 3:00 pm
- Room:
- AIBN building 75, Level 1 Seminar Room 132, St Lucia
- UQ Location:
- Australian Institute for Bioengineering and Nanotechnology (St Lucia)
- Event category(s):
Event Contact
- Name:
- Dr Christopher Noble
- Phone:
- 60360
- Email:
- c.noble@uq.edu.au
- Org. Unit:
- Advanced Imaging
Event Description
- Full Description:
- Professor STEVEN MEIKLE
Professor of Medical Imaging Physics
Head of Discipline, Medical Radiation Sciences
Course Director, Master of Molecular Imaging course
Faculty of Health Sciences and Brain & Mind Research Institute
THE UNIVERSITY OF SYDNEY
Open Field PET: Progress on systems for the simultaneous study of brain function and behaviour in small animals
Abstract: High resolution small animal PET has the potential to play an important role in understanding the molecular basis of cognition and behaviour under normal and pathological conditions. However, the routine use of anaesthesia imposes three crucial limitations: (i) it perturbs the neurological parameters of interest, including blood flow, receptor occupancy and neurotransmitter release, (ii) it precludes the study of neurochemical responses to sensory stimuli that require the animal’s conscious attention and (iii) it prohibits the recording of behavioural responses. This presentation will describe our progress towards the development of Open-Field PET – a technique that makes it feasible to image the brains of awake, unrestrained rodents using PET while simultaneously delivering controlled stimuli via an operant conditioning chamber and recording the animal’s behavioural outputs. Results of recent pilot studies demonstrating the utility of the technique will be presented and possible avenues for hypothesis testing in models of reward-driven learning and drug addiction will be explored.
Biosketch:
Steven Meikle is Professor of Medical Imaging Physics and Director of the University of Sydney/ANSTO node of the National Imaging Facility. He received his Bachelor of Applied Physics degree from the University of Technology, Sydney in 1988 and his Ph.D. degree from the Graduate School of Biomedical Engineering, University of New South Wales in 1995. He was a medical physicist at Royal Prince Alfred Hospital in Sydney from 1987-2004, a visiting research associate at the Division of Nuclear Medicine and Biophysics, UCLA School of Medicine from 1991-2 and a post doctoral research scientist at the MRC Cyclotron Unit in London from 1995-6 before joining the University of Sydney in 2004. Dr Meikle has published 7 book chapters and 180 research papers which have been cited more than 3,900 times in the scientific literature. He is a Fellow of the Australian Institute of Physics and a Senior Member of the IEEE. He serves on the Editorial Board of Physics in Medicine and Biology.
Directions to UQ
- Google Map:
-
- Directions:
- St Lucia Campus | Gatton campus.
Event Tools
Share This Event
Print
Email
Share
