Dr. Matthew Sweet (ARC Future Fellow and Honorary NHMRC Senior Research Fellow)

Matthew Sweet

Dr. Matthew Sweet studies the mechanisms by which the innate immune system responds to microbial challenge.

Cells of the innate immune system, such as macrophages, detect invading pathogens through pattern recognition receptors, in particular Toll-Like Receptors (TLRs).

TLRs are essential for the host response to invading pathogens, but can also contribute to the pathogenesis of many chronic disease states, such as atherosclerosis, systemic lupus erythematosus, and rheumatoid arthritis.

Dr. Sweet studies TLR signalling pathways and the functions of TLR target genes in the context of both infectious and inflammatory diseases.

Dr. Sweet is an ARC Future Fellow and an honorary NHMRC Senior Research Fellow.

Publications by Matthew Sweet

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